Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model
Adam Bohr, Nicolas Tsapis, Camilla Foged, Ilaria Andreana, Mingshi Yang, Elias Fattal
Topics & Concepts
Small interfering RNAIn vivoTumor necrosis factor alphaInflammationLipopolysaccharideTransfectionChemistryIn vitroGene silencingDendrimerPharmacologyImmunologyMedicineBiologyBiochemistryBiotechnologyGeneRNA Interference and Gene DeliveryDendrimers and Hyperbranched PolymersImmunotherapy and Immune Responses