TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
Leandro Venturutti, Matt Teater, Andrew Zhai, Amy Chadburn, Leena Babiker, Daleum Kim, Wendy Béguelin, Tak C. Lee, Youngjun Kim, Christopher R. Chin, William T. Yewdell, Brian Raught, Jude M. Phillip, Yanwen Jiang, Louis M. Staudt, Michael R. Green, Jayanta Chaudhuri, Olivier Elemento, Pedro Farinha, Andrew P. Weng, Michael Nissen, Christian Steidl, Ryan D. Morin, David W. Scott, Gilbert G. Privé, Ari Melnick
Topics & Concepts
BiologyGerminal centerBCL6ReprogrammingTranscription factorPhenotypeSomatic hypermutationCancer researchCell fate determinationSomatic cellLymphomaB cellCellCell biologyGeneGeneticsImmunologyAntibodyCAR-T cell therapy researchImmune Cell Function and InteractionLymphoma Diagnosis and Treatment