Kinetic resolution of sulfoxides with high enantioselectivity using a new homologue of methionine sulfoxide reductase B
Yuyan Zhao, Xu Jiang, Shihuan Zhou, Jin Tian, Piao Yang, Yanli Chen, Quan Zhang, Xianlin Xu, Yong‐Zheng Chen, Jiawei Yang
Abstract
A range of sulfoxides including aromatic, heteroaromatic, alkyl and thioalkyl sulfoxides in the S configuration were prepared through kinetic resolution catalyzed by a new MsrB enzyme.
Topics & Concepts
ChemistryKinetic resolutionSulfoxideYield (engineering)Substrate (aquarium)EnantiomerEnantiomeric excessStereochemistryResolution (logic)AlkylEnzymeOrganic chemistryEnantioselective synthesisCatalysisArtificial intelligenceGeologyMetallurgyOceanographyMaterials scienceComputer scienceEnzyme Catalysis and ImmobilizationMass Spectrometry Techniques and ApplicationsCholinesterase and Neurodegenerative Diseases