“Flash & Click”: Multifunctionalized Lipid Derivatives as Tools To Study Viral Infections
Carsten Schultz, Scotland Farley, Fikadu Tafesse
Abstract
In this perspective article, we describe the current status of lipid tools for studying host lipid-virus interactions at the cellular level. We discuss the potential lipidomic changes that viral infections impose on host cells and then outline the tools available and the resulting options to investigate the host cell lipid interactome. The future outcome will reveal new targets for treating virus infections.
Topics & Concepts
InteractomeChemistryHost (biology)VirusComputational biologyLipid metabolismVirologyBiochemistryBiologyEcologyGeneLipid Membrane Structure and Behaviorinterferon and immune responsesPeroxisome Proliferator-Activated Receptors