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SARS-CoV-2 viral load in sputum correlates with risk of COVID-19 progression

Yu Xia, Shanshan Sun, Yu Shi, Hao Wang, Ruihong Zhao, Jifang Sheng

2020Critical Care188 citationsDOIOpen Access PDF

Abstract

The pandemic of coronavirus diseases 2019 (COVID-19) imposes a heavy burden on medical resources [1]. Whether there is correlation between viral load and disease severity has not been clarified. In the study, we retrospectively collected the virological data, as well as demographic, epidemiological clinical information of 92 patients with confirmed COVID-19 in a single hospital in Zhejiang Province, China. We compared the baseline viral loads between severe patients and those mild to moderate at admission and also between those developing severe disease during hospitalization and those not.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakViral loadBetacoronavirusSputumVirologySars virusViral therapyIntensive care medicineInternal medicineTuberculosisHuman immunodeficiency virus (HIV)PathologyInfectious disease (medical specialty)DiseaseOutbreakCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchCOVID-19 diagnosis using AI
SARS-CoV-2 viral load in sputum correlates with risk of COVID-19 progression | Litcius