NLRP3 inflammasome activation in alveolar epithelial cells promotes myofibroblast differentiation of lung-resident mesenchymal stem cells during pulmonary fibrogenesis
Jie Ji, Jiwei Hou, Yunhui Xia, Zou Xiang, Xiaodong Han
Topics & Concepts
InflammasomePulmonary fibrosisMyofibroblastMesenchymal stem cellBleomycinLungDKK1Idiopathic pulmonary fibrosisMedicineFibrosisImmunologyCancer researchWnt signaling pathwayPathologyBiologyInflammationSignal transductionCell biologyInternal medicineChemotherapyInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisInflammasome and immune disordersChronic Obstructive Pulmonary Disease (COPD) Research