Simultaneous single-cell phenotype analysis of hepatocellular carcinoma CTCs using a SERS-aptamer based microfluidic chip
Rongke Gao, Changbiao Zhan, Chunyu Wu, Yang Lu, Baoqiang Cao, Jing Huang, Feng Wang, Liandong Yu
Abstract
. The results showed that the proposed strategy can successfully identify HCC cell subtypes by SERS measurements, which was related to the clinical surface biomarkers. This may open a new avenue for serving as a powerful tool of cancer diagnosis and prognosis evaluation.
Topics & Concepts
AptamerHepatocellular carcinomaMicrofluidic chipMicrofluidicsPhenotypeHepatic carcinomaCellCancer researchNanotechnologyChemistryMolecular biologyMaterials scienceBiologyBiochemistryGene3D Printing in Biomedical ResearchCancer Cells and MetastasisInnovative Microfluidic and Catalytic Techniques Innovation