Serine protease homolog pairs CLIPA4-A6, A4-A7Δ, and A4-A12 act as cofactors for proteolytic activation of prophenoloxidase-2 and -7 in Anopheles gambiae
Qiao Jin, Yang Wang, Yingxia Hu, Yan He, Chao Xiong, Haobo Jiang
Topics & Concepts
Manduca sextaProphenoloxidaseCofactorBiologyProteasesSerine proteaseAnopheles gambiaeBiochemistryProteaseSerineCatalytic triadMutantMolecular biologyInsectPhosphorylationEnzymeInnate immune systemGeneReceptorBotanyMalariaImmunologyInvertebrate Immune Response MechanismsInsect symbiosis and bacterial influencesInsect Resistance and Genetics