G-quadruplex-based aptamers targeting human thrombin: Discovery, chemical modifications and antithrombotic effects
Claudia Riccardi, Ettore Napolitano, Chiara Platella, Domenica Musumeci, Daniela Montesarchio
Topics & Concepts
AptamerThrombinOligonucleotideChemistryBiochemistryNucleic acidG-quadruplexDiscovery and development of direct thrombin inhibitorsDNACombinatorial chemistryMolecular biologyBiologyPlateletImmunologyAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry