Spinacetin alleviates doxorubicin-induced cardiotoxicity by initiating protective autophagy through SIRT3/AMPK/mTOR pathways
Dawei Liu, Lei Zhao
Topics & Concepts
AutophagyCardiotoxicityAMPKPI3K/AKT/mTOR pathwayDoxorubicinULK1SIRT3PharmacologyCancer researchChemistryMedicineSignal transductionApoptosisSirtuinKinaseProtein kinase AInternal medicineChemotherapyBiochemistryAcetylationGeneChemotherapy-induced cardiotoxicity and mitigationCancer Treatment and PharmacologyChemotherapy-induced organ toxicity mitigation