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Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs

Dingqiang Fu, Yi Yuan, Fengming Qin, Yan Xu, Xin Cui, Guangxun Li, Shaohua Yao, Yun Deng, Zhuo Tang

2021European Journal of Medicinal Chemistry22 citationsDOIOpen Access PDF

Topics & Concepts

TyrosinaseChemistryMelaninZebrafishPharmacologyBiochemistryEnzymeBiologyGeneProtein Degradation and InhibitorsReceptor Mechanisms and SignalingUbiquitin and proteasome pathways
Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs | Litcius