Litcius/Paper detail

Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a phase 2, randomized, placebo-controlled trial

Tien Dam, Adam L. Boxer, Lawrence I. Golbe, Günter U. Höglinger, Huw R. Morris, Irene Litvan, Anthony E. Lang, Jean‐Christophe Corvol, Ikuko Aiba, Michael Grundman, Lili Yang, Beth Tidemann‐Miller, Joseph Kupferman, Kristine D. Harper, Kubra Kamisoglu, Michael Wald, Danielle Graham, Liz Gedney, John O’Gorman, Samantha Budd Haeberlein, PASSPORT Study Group

2021Nature Medicine138 citationsDOI

Topics & Concepts

Progressive supranuclear palsyPlaceboDiscontinuationClinical endpointMedicineInternal medicineSurrogate endpointRandomized controlled trialAdverse effectClinical trialGastroenterologyPathologyDiseaseAlternative medicineParkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsBotulinum Toxin and Related Neurological Disorders