The effect of artesunate to reverse CLP-induced sepsis immunosuppression mice with secondary infection is tightly related to reducing the apoptosis of T cells via decreasing the inhibiting receptors and activating MAPK/ERK pathway
Yue Yuan, Hua Ling, Jun Zhou, Dan Liu, Fumin Ouyang, Xuemin Chen, Shujuan Long, Ya-Si Huang, Xin Liu, Jiang Zheng, Hong Zhou, Hong Zhou
Topics & Concepts
ArtesunateImmune systemCD8BiologyImmunosuppressionCytotoxic T cellImmunologyAcquired immune systemT cellSepsisPharmacologyIn vitroBiochemistryMalariaPlasmodium falciparumIntensive Care Unit Cognitive DisordersSepsis Diagnosis and TreatmentImmune Response and Inflammation