SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis
Kevin Tong, Om A. Kothari, Katherine S. Haro, Anshuman Panda, Manisha Bandari, Jillian N. Carrick, Joseph J. Hur, Lanjing Zhang, Chang S. Chan, Jinchuan Xing, Michael L. Gatza, Shridar Ganesan, Michael P. Verzi
Topics & Concepts
Wnt signaling pathwayBiologyCancer researchCarcinogenesisV600EMicrosatellite instabilityMutationColorectal cancerMLH1CancerDNA mismatch repairMSH2Tumor initiationGeneticsGeneMicrosatelliteAlleleGenetic factors in colorectal cancerColorectal Cancer Treatments and StudiesGastric Cancer Management and Outcomes