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Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons

Yongzhi Yang, Meghan Lee Arnold, Caitlin M. Lange, Ling-Hsuan Sun, Michael Broussalian, Saam Doroodian, Hiroshi Ebata, Elizabeth H. Choy, Karie Poon, Tatiana M. Moreno, Anupama Singh, Monica Driscoll, Caroline Kumsta, Malene Hansen

2024Nature Aging53 citationsDOIOpen Access PDF

Topics & Concepts

ProteostasisAutophagyBiologyCell biologyCaenorhabditis elegansGene knockdownGeneProtein aggregationBiogenesisGeneticsApoptosisGenetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and TherapyAging, Elder Care, and Social Issues
Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons | Litcius