Dynamic self-assembling supramolecular dendrimer nanosystems as potent antibacterial candidates against drug-resistant bacteria and biofilms
Dinesh Dhumal, Bar Maron, Einav Malach, Zhenbin Lyu, Ling Ding, Domenico Marson, Erik Laurini, Aura Tintaru, Brigino Ralahy, Suzanne Giorgio, Sabrina Pricl, Zvi Hayouka, Ling Peng
Abstract
The alarming and prevailing antibiotic resistance crisis urgently calls for innovative “outside of the box” antibacterial agents, which can differ substantially from conventional antibiotics.
Topics & Concepts
DendrimerAmphiphileSupramolecular chemistryAntibacterial activityChemistryContext (archaeology)NanotechnologyBiofilmBacterial cell structurePoly(amidoamine)Hydrophobic effectSelf-assemblyCombinatorial chemistryBacteriaBiophysicsMaterials scienceAmidoamineOrganic chemistryBiologyMoleculeCopolymerPaleontologyGeneticsPolymerAntimicrobial agents and applicationsDendrimers and Hyperbranched PolymersAntimicrobial Peptides and Activities