Recent Advances in the Chemistry and Application of SF5-Compounds
Vincent Bizet, Mariam Abd El Sater, Lucas Popek, Nicolas Blanchard
Abstract
Abstract This review article outlines the literature from 2022 to 2024 covering developments in SF5 chemistry. Recent synthetic methodologies of SF5-containing building blocks are reported. These methods include the synthesis of SF5Cl and its use in pentafluorosulfanylation reactions and oxidative fluorination reactions. Moreover, the reactivity of SF5-alkynes as versatile platform to access new SF5-compounds is described. Finally, the effects of the SF5 moiety are highlighted according to its application in different fields, such as biological/medicinal chemistry, catalysis, and material sciences. 1 Introduction 2 Access to SF5-Containing Building Blocks 2.1 By Means of SF5Cl 2.1.1 Generation of SF5Cl 2.2 By Means of Oxidative Fluorination 2.3 By Means of SF5-Alkynes 2.4 Other Miscellaneous Aromatic and Aliphatic SF5-Compounds 3 Applications 3.1 Medicinal and Biological Chemistry 3.2 Material Science 3.3 Catalysis 4 Conclusion