IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage
Telma Lança, Jonas Ungerbäck, Clément Da Silva, Thorsten Joeris, Fatemeh Ahmadi, Julien Vandamme, Marcus Svensson, Allan McI. Mowat, Knut Kotarsky, Mikael Sigvardsson, William W. Agace
Topics & Concepts
IRF8BiologyCyclin-dependent kinase 1IRF4Transcription factorInterferon regulatory factorsEpigeneticsChromatinReprogrammingCancer researchGeneticsCell biologyGeneCell cycleImmunotherapy and Immune ResponsesT-cell and B-cell Immunologyinterferon and immune responses