Copper-Mediated Deconstructive Ring Cleavage of Cyclic Thioethers with Boron Compounds
Guanyu Wang, Dongchang Han, Yue Li, Yangleiyu Nie, Selvaraj Muthusamy, Zhibin Luo, Bin Liu
Abstract
The deconstructive ring cleavage of cyclic thioethers is achieved through a Chan-Lam type process with boron compounds. The sequential hydroboration/ring cleavage process from alkynes offered a new route to the preparation of vinyl sulfides based on the developed conditions. Further exploration has demonstrated the versatility of nucleophiles, delivering various functionalized sulfides featuring linear frameworks.
Topics & Concepts
ChemistryHydroborationCleavage (geology)BoronNucleophileRing (chemistry)CopperCombinatorial chemistryPolymer chemistryOrganic chemistryStereochemistryCatalysisGeotechnical engineeringEngineeringFracture (geology)Sulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods