Low-intensity Pulsed Ultrasound regulates alveolar bone homeostasis in experimental Periodontitis by diminishing Oxidative Stress
Siqi Ying, Minmin Tan, Feng Ge, Yunchun Kuang, Duanjing Chen, Jie Li, Jinlin Song
Abstract
These results demonstrated that LIPUS regulates alveolar bone homeostasis in periodontitis by attenuating oxidative stress via the regulation of PI3K-Akt/Nrf2 signaling. Thus, Nrf2 plays a pivotal role in the protective effect exerted by LIPUS against ligature-induced experimental periodontitis.
Topics & Concepts
Oxidative stressDental alveolusPeriodontitisChemistryLow-intensity pulsed ultrasoundViability assayBone resorptionPI3K/AKT/mTOR pathwayPharmacologyMedicineInternal medicineApoptosisBiochemistryDentistryTherapeutic ultrasoundUltrasoundRadiologyOral microbiology and periodontitis researchLaser Applications in Dentistry and MedicineOral Health Pathology and Treatment