YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
Srimayee Vaidyanathan, Talhah M. Salmi, Rasan M Sathiqu, Malcolm J. McConville, Andrew G. Cox, Kristin Brown
Topics & Concepts
LipogenesisBiologySterol regulatory element-binding proteinmTORC1Cell biologyHippo signaling pathwayPI3K/AKT/mTOR pathwayCell growthSGK1Fatty acid synthaseEffectorLipid metabolismSignal transductionTranscription factorKinaseBiochemistryGeneHippo pathway signaling and YAP/TAZLipid metabolism and biosynthesisCancer, Lipids, and Metabolism