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Synthesis, characterisation and biological evaluation of monometallic Re(<scp>i</scp>) and heterobimetallic Re(<scp>i</scp>)/Fe(<scp>ii</scp>) complexes with a 1,2,3-triazolyl pyridine chelating moiety

Silvio Jakopec, Lisa Gourdon, Ivona Čipor, Andrijana Meščić, Berislav Perić, Ivo Piantanida, Kevin Cariou, Gilles Gasser, Srećko I. Kirin, Silvana Raić‐Malić

2023Dalton Transactions12 citationsDOIOpen Access PDF

Abstract

Heterobimetallic Re( i ) ferrocene dipyridylamine complexes showed antiproliferative effects comparable to cisplatin on colon cancer cells, whereas the Re( i ) benzimidazo[1,2- a ]quinoline complex accumulated in lysosomes and interacted with biomolecules.

Topics & Concepts

ChemistryMoietyQuinolineFerroceneChelationPyridineBiomoleculeStereochemistryCombinatorial chemistryMedicinal chemistryBiochemistryOrganic chemistryPhysical chemistryElectrodeElectrochemistryFerrocene Chemistry and ApplicationsMetal complexes synthesis and propertiesSynthesis and Biological Evaluation
Synthesis, characterisation and biological evaluation of monometallic Re(<scp>i</scp>) and heterobimetallic Re(<scp>i</scp>)/Fe(<scp>ii</scp>) complexes with a 1,2,3-triazolyl pyridine chelating moiety | Litcius