Single-cell RNA sequencing reveals a unique pericyte type associated with capillary dysfunction
Min Xia, Lyu Jiao, Xiaohan Wang, Min Tong, Mu‐Di Yao, Xiu‐Miao Li, Jin Yao, Dan Li, Peiquan Zhao, Biao Yan
Abstract
These findings enhance the understanding of the complexity and heterogeneity of retinal cells and have important implications for future treatment of capillary dysfunction.
Topics & Concepts
PericyteBiologyGene silencingTranscriptomePopulationCell typeCell biologyRetinalDownregulation and upregulationCellEndothelial stem cellPathologyMolecular biologyGene expressionGeneGeneticsIn vitroMedicineBiochemistryEnvironmental healthBarrier Structure and Function StudiesSingle-cell and spatial transcriptomicsAngiogenesis and VEGF in Cancer