<i>In situ</i>-crosslinked hydrogel-induced experimental glaucoma model with persistent ocular hypertension and neurodegeneration
Jicheng Lin, Jingfei Xue, Qian Xu, Zhe Liu, Chunyu Zhao, Jiahui Tang, Jiaxu Han, A Sigen, Wenxin Wang, Yehong Zhuo, Yiqing Li
Abstract
-forming HB-PEG/HA-SH hydrogel system could be an appropriate strategy for developing a reliable experimental glaucoma model without any confounding factors. We expect this model would be conducive to the development of neuroprotective and neuro-regenerative therapies.
Topics & Concepts
ElectroretinographyOphthalmologyIntraocular pressureScotopic visionMedicineRetinal ganglion cellGlaucomaOcular hypertensionNeurodegenerationNeuroprotectionRetinaOptic nerveRetinalNeurosciencePathologyPharmacologyDiseaseBiologyGlaucoma and retinal disordersOcular Surface and Contact LensRetinal Diseases and Treatments