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Phosphine-Catalyzed Dearomative [3 + 2] Cycloaddition of Benzoxazoles with a Cyclopropenone

Xingben Wang, Congjun Yu, Iuliana Atodiresei, Frédéric W. Patureau

2022Organic Letters27 citationsDOIOpen Access PDF

Abstract

The triphenylphosphine-catalyzed dearomative [3 + 2] cycloaddition of benzoxazoles with 1,2-diphenylcyclopropenone is herein described. The reaction scope, mechanism, and possible future applications of this rare organocatalyzed cycloaddition are herein discussed.

Topics & Concepts

CycloadditionChemistryPhosphineCatalysisTriphenylphosphineScope (computer science)Combinatorial chemistryOrganic chemistryComputer scienceProgramming languageCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsCatalytic Alkyne Reactions
Phosphine-Catalyzed Dearomative [3 + 2] Cycloaddition of Benzoxazoles with a Cyclopropenone | Litcius