Positive selection of IgG+ over IgM+ B cells in the germinal center reaction
Christopher Sundling, Angelica W.Y. Lau, Katherine Bourne, Clara Young, Candy Laurianto, Jana R. Hermes, Rosemary J. Menzies, Danyal Butt, Nike Julia Kräutler, David Zahra, Dan Suan, Robert Brink
Topics & Concepts
Somatic hypermutationGerminal centerAffinity maturationBiologyImmunoglobulin class switchingAntibodyB cellMolecular biologyImmunoglobulin MAntigenB-cell receptorCD40Immunoglobulin GImmunologyGeneticsIn vitroCytotoxic T cellT-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies ResearchImmune Cell Function and Interaction