Novel derivatives of eugenol as potent anti-inflammatory agents <i>via</i> PPARγ agonism: rational design, synthesis, analysis, PPARγ protein binding assay and computational studies
Noor Fathima Anjum, Dhivya Shanmugarajan, Vasanth Kumar Shivaraju, Syed Faizan, Namburu Lalitha Naishima, B. R. Prashantha Kumar, Saleem Javid, Madhusudan Purohit
Abstract
Rational design, synthesis, analysis, PPARγ protein binding assay and computational studies of novel eugenol derivatives.
Topics & Concepts
EugenolChemistryRational designPharmacologyAgonismPeroxisome proliferator-activated receptorCombinatorial chemistryStereochemistryBiochemistryReceptorMedicineNanotechnologyOrganic chemistryLawMaterials sciencePoliticsPolitical sciencePeroxisome Proliferator-Activated ReceptorsInflammatory mediators and NSAID effectsCholesterol and Lipid Metabolism