Ratiometric imaging of butyrylcholinesterase activity in mice with nonalcoholic fatty liver using an AIE-based fluorescent probe
Chunbai Xiang, Jingjing Xiang, Yang Xing, Chunbin Li, Lihua Zhou, Daoyong Jiang, Yonglin Peng, Zhen Xu, Guanjun Deng, Baode Zhu, Pengfei Zhang, Lintao Cai, Ping Gong
Abstract
) and specificity for BChE. Moreover, we have successfully studied the ratiometric imaging of TB-BChE to BChE in a nonalcoholic fatty liver disease model. These results indicated that TB-BChE is expected to become a powerful analysis tool for butyrylcholinesterase research in basic medicine and clinical applications.
Topics & Concepts
ButyrylcholinesteraseFluorescenceNonalcoholic fatty liver diseaseMaterials scienceChemistryMedicineBiochemistryInternal medicineFatty liverEnzymeOpticsAchéPhysicsDiseaseAcetylcholinesteraseCholinesterase and Neurodegenerative DiseasesNicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research