Hybrid system {W<sub>6</sub>I<sub>8</sub>}-cluster/dsDNA as an agent for targeted X-ray induced photodynamic therapy of cancer stem cells
Tatiana N. Pozmogova, Natalya A. Sitnikova, Е. В. Пронина, Светлана Мирошниченко, A. O. Kushnarenko, Anastasiya O. Solovieva, С. С. Богачев, Georgy D. Vavilov, Olga A. Efremova, Yuri A. Vorotnikov, Michael A. Shestopalov
Abstract
The hybrid material W 6 -cluster/dsDNA designed here demonstrates selective penetration into cancer stem cells and their targeted elimination using X-PDT.
Topics & Concepts
Photodynamic therapyCluster (spacecraft)Materials scienceCancer researchNanotechnologyMedicineChemistryComputer scienceOrganic chemistryProgramming languageInorganic Chemistry and MaterialsNanoplatforms for cancer theranosticsNanocluster Synthesis and Applications