Implications of ligand-receptor binding kinetics on GLP-1R signalling
Peishen Zhao, Tin T. Truong, Jon Merlin, Patrick M. Sexton, Denise Wootten
Topics & Concepts
G protein-coupled receptorReceptorReceptor–ligand kineticsAgonistGlucagon-like peptide 1 receptorLigand (biochemistry)ChemistryPeptideFunctional selectivitySignal transductionG proteinCell biologyBiochemistryBiologyBiophysicsDiabetes Treatment and ManagementReceptor Mechanisms and SignalingNeuropeptides and Animal Physiology