Combined induction of mTOR-dependent and mTOR-independent pathways of autophagy activation as an experimental therapy for Alzheimer's disease-like pathology in a mouse model
А. Б. Пупышев, В. М. Беличенко, М. В. Тендитник, Alim A. Bashirzade, Н. И. Дубровина, M. V. Ovsyukova, Anna A. Akopyan, Larisa Fedoseeva, Т. А. Короленко, Tamara G. Amstislavskaya, М. А. Тихонова
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwayNeurodegenerationMicrogliaBECN1NeuroprotectionMechanistic target of rapamycinInducerCell biologyAmyloid betaHippocampusATG8ChemistryBiologyPharmacologyMedicineNeuroscienceInternal medicineSignal transductionImmunologyInflammationBiochemistryApoptosisGeneDiseaseAlzheimer's disease research and treatmentsAutophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments