Protective ApoE variants support neuronal function by effluxing oxidized phospholipids
Isha Ralhan, D. Alison, Ju-Young Bae, Femke M. Feringa, Wendy Cai, Jinlan Chang, Ki Wai Chik, Nathanael Y.J. Lee, Christopher J Gerry, Rik van der Kant, Jesse Jackson, Emily L. Ricq, Maria S. Ioannou
Topics & Concepts
Apolipoprotein EFunction (biology)Cell biologyChemistryApolipoprotein BLipoproteinCholesterolNeurodegenerationBiochemistryLipid metabolismAxoplasmic transportNeuroscienceBiologyGene isoformAffect (linguistics)Premovement neuronal activityLoss functionFerroptosis and cancer prognosisCholesterol and Lipid MetabolismAlzheimer's disease research and treatments