Potent nanoreactor-mediated ferroptosis-based strategy for the reversal of cancer chemoresistance to Sorafenib
Xiaorui Wang, Lei Zhao, Chenxi Wang, Leichen Wang, Haisi Wu, Xuejiao Song, Wenjun Wang, Huae Xu, Xiaochen Dong
Topics & Concepts
GPX4GlutathioneCancer cellLipid peroxidationChemistryOxidative stressIntracellularProgrammed cell deathDownregulation and upregulationGlutathione peroxidaseCell biologyBiochemistryCancer researchCancerApoptosisBiologyEnzymeGeneticsGeneNanoplatforms for cancer theranosticsFerroptosis and cancer prognosisInflammatory mediators and NSAID effects