Design, synthesis and evaluation of a myricetin and nobiletin hybrid compound for alleviating hyperuricemia based on metabolomics and gut microbiota
Yan Li, Liu‐Yang Pu, Yayun Li, Guanbao Zhu, Zhengzhi Wu
Abstract
A hybrid compound consisting of myricetin and nobiletin (MNH) was designed and synthesized, which might represent a protective effect against HUA via modulating the gut microbiota composition and serum metabolite profile.
Topics & Concepts
MyricetinNobiletinHyperuricemiaMetabolomicsGut floraChemistryUric acidQuercetinBiochemistryChromatographyKaempferolFlavonoidAntioxidantGout, Hyperuricemia, Uric AcidPharmacological Effects of Natural CompoundsGinseng Biological Effects and Applications