Novel Benzo[4,5]imidazo[1,2-a]pyrimidine derivatives as selective Cyclooxygenase-2 Inhibitors: Design, synthesis, docking studies, and biological evaluation
Maryam Bayanati, Mona Khoramjouy, Mehrdad Faizi, Mahsa Azami Movahed, Mohammad Mahboubi‐Rabbani, Afshin Zarghi
Topics & Concepts
ChemistryPharmacophorePyrimidineIn vivoStereochemistryDocking (animal)CyclooxygenaseAutoDockIC50PharmacologyIn vitroEnzymeBiochemistryIn silicoNursingMedicineGeneBiologyBiotechnologySynthesis and biological activityInflammatory mediators and NSAID effectsSynthesis of β-Lactam Compounds