Activation and regulation of NAIP/NLRC4 and NLRP3 inflammasomes during Salmonella infection: mechanisms and therapeutic implications
Yan He, Dandan Ding, Jiayin Guo, Hui Sun, Jing Yang
Topics & Concepts
InflammasomeContext (archaeology)Innate immune systemNLRC4BiologyFlagellinCell biologyImmune systemAIM2Pyrin domainSignal transductionSalmonellaLipopolysaccharideAcetylationEpigeneticsInflammationPathogenic bacteriaTLR4Computational biologyHost (biology)Signalling pathwaysProinflammatory cytokineEffectorImmunityPosttranslational modificationMitochondrionInflammasome and immune disordersEndoplasmic Reticulum Stress and DiseaseCell death mechanisms and regulation