Case Fatality Rate of COVID-19: A Systematic Review and Meta-Analysis
Mojtaba Sepandi, Yousef Alimohamadi, Hailu Tola, Habteyes, Abbas Abbasi-Ghahramanloo, Majid Janani
Abstract
OBJECTIVE: The ongoing novel coronavirus disease 2019 (COVID-19) is the leading cause of morbidity and mortality due to its contagious nature and absence of vaccine and treatment. Although numerous primary studies reported extremely variable case fatality rate (CFR) of COVID-19, no review study attempted to estimate the CFR of COVID-19. The current systematic review and meta-analysis were aimed to assess the pooled CFR of COVID-19. METHODS: were used to assess the functional heterogeneity between included studies. RESULTS: = 99.8). CONCLUSION: The present review results highlighted the need for transparency in testing and reporting policies and denominators used in CFR estimation. It is also necessary to report the case's age, sex, and the comorbidity distribution of all patients, which essential in comparing the CFR among different segments of the population.