Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases
George D. Lampe, Rebeca T. King, Tyler S. Halpin-Healy, Sanne E. Klompe, Marcus I. Hogan, Phuc Leo H. Vo, Stephen Tang, Alejandro Chavez, Samuel H. Sternberg
Topics & Concepts
TransposaseCRISPRDNAGeneticsBiologyComputational biologyTransposable elementGeneGenomeCRISPR and Genetic EngineeringPluripotent Stem Cells ResearchChromosomal and Genetic Variations