Pathogen evolution during vaccination campaigns
Troy Day, David Kennedy, Andrew F. Read, Sylvain Gandon
Abstract
Following the initiation of the unprecedented global vaccination campaign against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), attention has now turned to the potential impact of this large-scale intervention on the evolution of the virus. In this Essay, we summarize what is currently known about pathogen evolution in the context of immune priming (including vaccination) from research on other pathogen species, with an eye towards the future evolution of SARS-CoV-2.
Topics & Concepts
BiologyVaccinationPathogenContext (archaeology)VirologyImmunologyPaleontologySARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesCOVID-19 epidemiological studies