Ru-Catalyzed Defluorinative Alkylation or Catalyst-Free Hydroalkylation of <i>gem</i>-Difluoroalkenes Enabled by Visible Light
Fangran Liu, Zhen Zhuang, Qun Qian, Xiaofei Zhang, Chunhao Yang
Abstract
A catalyst-induced defluorinative, alkylation or metal-free hydroalkylation of gem-difluoroalkenes enabled by visible light was developed. This protocol provided a mild and practical approach to important and novel monofluoroalkenes and difluoromethylene-containing compounds with moderate to excellent yields.
Topics & Concepts
AlkylationCatalysisChemistryVisible spectrumCombinatorial chemistryOrganic chemistryMaterials scienceOptoelectronicsFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsRadical Photochemical Reactions