Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer
Zheng Zhang, Menglan Lu, Cailong Chen, Xing Tong, Yunhong Li, Kai Yang, Haitao Lv, Jiaying Xu, Li‐Qiang Qin
Abstract
Holo-Lf could induce ferroptosis in MDA-MB-231 cells and sensitize MDA-MB-231 tumors to radiotherapy.
Topics & Concepts
ChemistryLactoferrinLipid peroxidationTriple-negative breast cancerReactive oxygen speciesCancer researchMalondialdehydeHepcidinCancer cellOxidative stressBreast cancerCancerBiochemistryImmunologyInternal medicineMedicineInflammationFerroptosis and cancer prognosisRNA modifications and cancerCancer-related molecular mechanisms research