Litcius/Paper detail

High CO2 levels drive the TCA cycle backwards towards autotrophy

Lydia Steffens, Eugenio Pettinato, Thomas Steiner, Achim Mall, Simone König, Wolfgang Eisenreich, Ivan A. Berg

2021Nature191 citationsDOI

Topics & Concepts

Citric acid cycleCitrate synthaseCarbon fixationBiochemistryATP synthaseAutotrophCarboxylationPyruvate dehydrogenase complexChemistryOxidative phosphorylationAcetyl-CoATricarboxylic acidPyruvate carboxylaseMetabolismBiologyEnzymeBacteriaPhotosynthesisCatalysisGeneticsMicrobial Metabolic Engineering and BioproductionEnzyme Structure and FunctionProtein Structure and Dynamics