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Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes

Marieke Lavaert, Kai Ling Liang, Niels Vandamme, Jong-Eun Park, Juliette Roels, Monica S. Kowalczyk, Bo Li, Orr Ashenberg, Marcin Tabaka, Danielle Dionne, Timothy L. Tickle, Michal Slyper, Orit Rozenblatt–Rosen, Bart Vandekerckhove, Georges Leclercq, Aviv Regev, Pieter Van Vlierberghe, Martin Guilliams, Sarah A. Teichmann, Yvan Saeys, Tom Taghon

2020Immunity141 citationsDOIOpen Access PDF

Topics & Concepts

BiologyThymocyteHaematopoiesisProgenitor cellHoming (biology)ImmunologyTranscription factorPopulationCell biologyDendritic cellBone marrowStem cellT cellGeneImmune systemGeneticsEcologySociologyDemographySingle-cell and spatial transcriptomicsT-cell and B-cell ImmunologyImmune Cell Function and Interaction
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes | Litcius