Synthesis and biological evaluation of pentacyclic triterpenoid derivatives as potential novel antibacterial agents
Panpan Wu, Borong Tu, Jinfeng Liang, Shengzhu Guo, Nana Cao, Silin Chen, Zhujun Luo, Jia-Hao Li, Wende Zheng, Xiaowen Tang, Dongli Li, Xue-Tao Xu, Wenfeng Liu, Xi Zheng, Zhaojun Sheng, Adam P. Roberts, Kun Zhang, W. David Hong
Topics & Concepts
ChemistryAntibacterial activityUrsolic acidDNA gyraseStereochemistryOleanolic acidCytotoxicityStaphylococcus aureusIn vitroCombinatorial chemistryBiochemistryBacteriaEscherichia coliChromatographyBiologyGenePathologyAlternative medicineGeneticsMedicineNatural product bioactivities and synthesisPharmacological Effects of Natural CompoundsToxin Mechanisms and Immunotoxins