Novel chitosan and bacterial cellulose biocomposites tailored with polymeric nanoparticles for modern wound dressing development
Paul Octavian Stãnescu, Ionut‐Cristian Radu, Rebeca Leu Alexa, Ariana Hudiță, Eugenia Tanasă, Jana Ghițman, Oana Stoian, Aristidis Tsatsakis, Octav Ginghină, Cătălin Zaharia, Mikhail Shtilman, Yaroslav Mezhuev, Bianca Gălățeanu
Abstract
release behaviors of silver sulfadiazine from polymeric nanoparticles and biocomposites were investigated. The biological investigations revealed good biocompatibility of both the nanoparticles and the biocomposites in terms of human dermal fibroblasts viability and proliferation potential. Finally, the drug-loaded polymeric biomaterials showed promising characteristics, proving their high potential as an alternative support to develop a biocompatible and antibacterial wound dressing.
Topics & Concepts
ChitosanMaterials scienceBiocompatibilityBacterial celluloseSilver sulfadiazineCellulosePolyvinyl alcoholNanoparticleFourier transform infrared spectroscopyDrug deliveryChemical engineeringNanotechnologyWound healingComposite materialMedicineMetallurgyEngineeringImmunologyWound Healing and TreatmentsNanocomposite Films for Food PackagingElectrospun Nanofibers in Biomedical Applications