Sensitizing cancer cells to immune checkpoint inhibitors by microbiota-mediated upregulation of HLA class I
Valentina Ferrari, Antonino Lo Cascio, Alessia Melacarne, Nina Tanasković, Alessandro M. Mozzarelli, Luca Tiraboschi, Michela Lizier, M Salvi, Daniele Braga, Francesca Algieri, Giuseppe Penna, María Rescigno
Topics & Concepts
CTL*Cytotoxic T cellImmune systemDownregulation and upregulationCancer immunotherapyCancer researchImmunologyBiologyCancerHuman leukocyte antigenImmune checkpointEffectorImmunotherapyContext (archaeology)Cancer cellAntigenIn vitroCD8BiochemistryGeneticsGenePaleontologyCancer Immunotherapy and BiomarkersImmune cells in cancerGut microbiota and health