The <i>N,N,O</i>-Trisubstituted Hydroxylamine Isostere and Its Influence on Lipophilicity and Related Parameters
Jarvis Hill, David Crich
Abstract
-trisubstituted hydroxylamine moiety in small-molecule optimization schemes in medicinal chemistry.
Topics & Concepts
LipophilicityIsostereHydroxylamineChemistryMedicinal chemistryOrganic chemistryFluorine in Organic ChemistryChemical Reaction MechanismsEicosanoids and Hypertension Pharmacology