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An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells

Simona Ceglia, Alyssa Berthelette, Kelsey Howley, Yun Li, Benedikt M. Mortzfeld, Shakti K. Bhattarai, Nicole K.H. Yiew, Ying Xu, Robert Brink, Jason G. Cyster, Lora V. Hooper, Gwendalyn J. Randolph, Vanni Bucci, Andrea Reboldi

2023Nature Immunology48 citationsDOIOpen Access PDF

Topics & Concepts

SecretionBiologyImmune systemPlasma cellImmunoglobulin ALamina propriaAntibodyCell biologyImmunologyMemory B cellB cellImmunoglobulin GEndocrinologyEpitheliumGeneticsCholesterol and Lipid MetabolismImmune Cell Function and InteractionT-cell and B-cell Immunology
An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells | Litcius