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Endophytic Fungal Diversity and Its Interaction Mechanism with Medicinal Plants

Yuan Gao, Yan Xu, Zhijia Dong, Yuyang Guo, Jianghan Luo, Fuling Wang, Lijun Yan, Xiang Zou

2025Molecules29 citationsDOIOpen Access PDF

Abstract

This paper reviewed the diversity of endophytic fungi and their interactions with medicinal plants, along with the research methodologies utilized to investigate these interactions. It mainly includes the diversity of endophytic fungi, as well as distribution diversity, species diversity, and the diversity of their metabolites and functions, including antibacterial, anti-inflammatory, anti-tumor, insecticidal, antioxidant capabilities, and so on. The research methodologies employed to investigate the interactions between endophytic fungi and medicinal plants are categorized into metagenomics, transcriptomics, metatranscriptomics, proteomics, and metabolomics. Furthermore, this study anticipates the potential applications of secondary metabolites derived from endophytic fungi in both medicine and agriculture.

Topics & Concepts

Plant use of endophytic fungi in defenseBiologyMetagenomicsDiversity (politics)MetabolomicsMechanism (biology)Computational biologyBotanyBioinformaticsGeneBiochemistryEpistemologyPhilosophyAnthropologySociologyMicrobial Natural Products and BiosynthesisFungal Biology and ApplicationsPlant and fungal interactions
Endophytic Fungal Diversity and Its Interaction Mechanism with Medicinal Plants | Litcius