Screening of a short chain antimicrobial peptide-FWKFK and its application in wound healing
Runfeng Zhang, Han Yan, Xijie Wang, Hailin Cong, Bing Yu, Youqing Shen
Abstract
. Its biocompatibility and therapeutic effect on mouse wounds were then tested. The results showed that the survival rate of normal cells after FWKFK treatment was more than 95%, the hemolysis rate of red blood cells was as low as 6%, and it had a significant effect on wound healing in mice.
Topics & Concepts
AntimicrobialHemolysisAntimicrobial peptidesMicrobiologyMinimum inhibitory concentrationPeptideWound healingBacteriaAntibioticsChemistryAntibacterial activityMicroorganismBiologyBiochemistryImmunologyGeneticsAntimicrobial Peptides and ActivitiesAntimicrobial agents and applicationsProtein Hydrolysis and Bioactive Peptides